Side effects of Tramadol 100

Tramadol 100 mg:

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Tramadol 100 side-effects in summary

Commonly reported side effects of tramadol 100 to include: pruritus, agitation, anxiety, constipation, diarrhea, hallucination, nausea, tremor, vomiting, and diaphoresis. Other side effects of tramadol 100 include insomnia. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to tramadol 100: oral capsule extended release, oral suspension, oral tablet, oral tablet disintegrating, oral tablet extended the release

Along with its needed effects, tramadol 100 mg may also cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tramadol 100 mg:

Less common side effects of tramadol 100 mg:

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Buy-tramadol-100-mg-overnight
  • Abnormal or decreased touch sensation;
  • blisters under the skin;
  • bloating and, blood in the urine;
  • blood pressure increased;
  • blurred vision and so change in walking and balance;
  • chest pain or discomfort and likewise chills;
  • darkened urine and also difficult urination, frequent urge to urinate;
  • dizziness or lightheadedness when getting up from a lying or sitting position;
  • gaseous abdominal or stomach pain and also indigestion;
  • irregular and fast heartbeat;
  • loss of memory;
  • numbness and tingling of the face, fingers, or toes;
  • pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion;
  • pain or discomfort in the arms, jaw, back, or neck;
  • pains in the stomach, side, or abdomen, possibly radiating to the back;
  • pale, bluish-colored or cold hands or feet;
  • recurrent fever, fainting;
  • seeing, hearing, or feeling things that are not there;
  • seizures, severe cramping and also nausea;
  • severe redness, swelling, and itching of the skin;
  • stomach fullness, sweating;
  • trembling and shaking of the hands or feet;
  • trouble performing routine tasks;
  • weak or absent pulses in the legs;
  • yellow eyes or skin;

Get emergency help immediately if any of the following symptoms of overdose occur while taking tramadol 100:

Symptoms of Overdose 0f tramadol:

  • Change in consciousness;
  • also likewise decreased awareness or responsiveness;
  • difficulty with breathing;
  • lack of muscle tone and likewise lightheadedness;
  • loss of consciousness;
  • pinpointed pupils of the eyes;
  • severe sleepiness;
  • slow or irregular heartbeat;
  • unusual tiredness;

Some side effects of tramadol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common side effects of tramadol 100:

  • Agitation, constipation, cough, diarrhea, discouragement, and likewise drowsiness also;
  • dry mouth, feeling of warmth, getting sad or empty,feeling unusually cold, and fever;
  • a general feeling of discomfort or illness, headache, heartburn, irritability etc;
  • itching or skin rash, joint pain, loss of appetite, and likewise loss of interest or pleasure;
  • lossness of strength or weakness, muscle aches and pains, also likewise nausea symptoms;
  • redness of the face, neck, arms, and occasionally, upper chest; restlessness;
  • runny nose, shivering, sleepiness or likewise unusual drowsiness;
  • sore throat, stomach pain, stuffy nose, sweating and likewise tiredness;
  • trouble concentrating, an unusual feeling of excitement, and weakness;

Less common side effects of tramadol 100:

  • Abnormal dreams, appetite decreased, likewise back pain and bladder pain;
  • blistering, crusting, irritation, itching, or reddening of the skin, and also bloody or cloudy urine;
  • body aches or pain, change in hearing, clamminess, cold flu-like symptoms;
  • confusion, cough producing mucus, cracked, dry, or scaly skin and sometimes also decreased interest in sexual intercourse;
  • difficult, burning, or likewise painful urination, difficulty with moving, disturbance in attention;
  • ear congestion and also ear drainage, earache or pain in the ear;
  • excessive gas, falls, false or unusual sense of well-being;
  • feeling hot, feeling jittery, a general feeling of bodily discomfort;
  • goosebumps, headache, severe and throbbing, hoarseness, and likewise hot flashes;
  • inability to have or keep an erection, itching, pain, redness, swelling, tenderness, or warmth on the skin;
  • joint sprain, stiffness, or swelling, also loss in sexual ability, desire, drive, or performance;
  • loss of voice, likewise lower back or side pain;
  • muscle aching or cramping, and injury, muscle pain, stiffness, spasms, or likewise twitching;
  • nasal congestion, neck pain, night sweats and pain in the limbs and also pain or tenderness around the eyes and cheekbones;
  • pain, swelling, and also redness in the joints, skin discoloration;
  • swelling; swelling of the hands, ankles, feet, or lower legs;
  • the tightness of the chest, trouble in holding or releasing urine, trouble with sleeping; and also weight increased or decreased;

For Healthcare Professionals

Applies to tramadol 100: oral capsule extended release, oral tablet, oral tablet disintegrating, oral tablet extended the release

General

The most common adverse reactions include nausea, constipation, dry mouth, somnolence, dizziness, and vomiting.

Psychiatric

CNS stimulation has been reported as a composite of nervousness, anxiety, agitation, tremor, spasticity, euphoria, emotional lability, and hallucinations. During clinical trials, tolerance development was mild and the reports of a withdrawal syndrome were rare. Symptoms of a withdrawal syndrome have included: panic attacks, severe anxiety, hallucinations, paraesthesias, tinnitus and unusual CNS symptoms (i.e. confusion, delusions, personalization, derealization, and paranoia).

Very common (10% or more): CNS stimulation (up to 14%)

Common (1% to 10%): Anxiety, euphoria, nervousness, sleep disorder, insomnia, depression, agitation, apathy, depersonalization

Uncommon (0.1% to 1%): Emotional lability

Rare (less than 0.1%): Hallucinations, nightmares, dependency

Very rare (less than 0.01%): Withdrawal syndrome

Hypersensitivity

Rare (less than 0.1%): Anaphylaxis, allergic reactions such as dyspnea, bronchospasm, wheezing, angioneurotic edema, swollen skin

Gastrointestinal

Very common (10% or more): Nausea (up to 40%), constipation (up to 46%), vomiting (up to 17%), dyspepsia (up to 13%)

Common (1% to 10%): Dry mouth, diarrhea, abdominal pain, flatulence, sore throat, gastroenteritis viral

Uncommon (0.1% to 1%): Toothache, appendicitis, pancreatitis

Nervous system

Epileptiform seizures primarily occurred following administration of high doses or following concomitant treatment with drugs that lower the seizure threshold or trigger seizures.

Serotonin syndrome has been reported during concomitant use of opioids with serotonergic drugs.

Very common (10% or more): Dizziness (up to 28%), somnolence (up to 25%), headache (up to 32%),

Common (1% to 10%): Confusion, coordination disturbance, tremor, paresthesia, hypoesthesia

Uncommon (0.1% to 1%): Migraine, sedation, syncope, disturbance in attention

Rare (less than 0.1%): Epileptiform seizures

Postmarketing reports: Seizures

Opioids:

Postmarketing reports: Serotonin syndrome

Dermatologic

Very common (10% or more): Pruritus (up to 11%)

Common (1% to 10%): Sweating, rash, dermatitis

Uncommon (0.1% to 1%): Cellulitis, piloerection, clamminess, urticaria, toxic epidermal necrolysis, Stevens Johnson-syndrome, hair disorder, skin disorder

Genitourinary

Common (1% to 10%): Menopausal symptoms, urinary frequency, urinary retention, urinary tract infection

Uncommon (0.1% to 1%): Difficulty in micturition, hematuria, dysuria, cystitis, sexual function abnormality

Cardiovascular

Reports of QT prolongation and/or torsade de points have been received. In many cases, patients were taking another drug associated with QT prolongation, had risk factors for QT prolongation such as hypokalemia, or in the overdose setting.

Very common (10% or more): Flushing (up to 15.8%)

Common (1% to 10%): Vasodilation, postural hypotension, chest pain

Uncommon (0.1% to 1%): Palpitations, myocardial infarction, lower limb edema, peripheral swelling, hypertension, increased heart rate, peripheral ischemia, EKG abnormality, hypotension, tachycardia

Rare (less than 0.1%): Bradycardia

Postmarketing reports: QT prolongation/torsade de points

Other

Very common (10% or more): Asthenia (up to 12%)

Common (1% to 10%): Malaise, weakness, pain, feeling hot, influenza-like illness, rigors, lethargy, pyrexia

Uncommon (0.1% to 1%): Tinnitus, vertigo, ear infection

Metabolic

Common (1% to 10%): Anorexia, decreased weight, increased blood glucose

Uncommon (0.1% to 1%): Gout

Rare (less than 0.1%): Changes in appetite

Endocrine

Very rare (less than 0.01%): Syndrome of inappropriate antidiuretic hormone secretion

Opioids:

Postmarketing reports: Adrenal insufficiency; androgen deficiency

Hematologic

Uncommon (0.1% to 1%): Anemia, ecchymosis

Hepatic

Uncommon (0.1% to 1%): Cholelithiasis, cholecystitis, ALT and AST increased, abnormal liver function tests[Ref]

Ocular

Common (1% to 10%): Miosis, visual disturbance, blurred vision

Uncommon (0.1% to 1%): Lacrimation disorder

Frequency not reported: Mydriasis

Renal

Uncommon (0.1% to 1%): blood urea nitrogen increased

Musculoskeletal

Common (1% to 10%): Hypertonia, arthralgia, back pain, limb pain, neck pain, muscle cramps, muscle spasms, joint stiffness, muscle twitching, myalgia, aggravated osteoarthritis

Uncommon (0.1% to 1%): Joint swelling, joint sprain, muscle injury, leg cramps

Rare (less than 0.1%): Involuntary muscle contractions

References

1. Cerner Multum, Inc. “UK Summary of Product Characteristics.” O 0

2. Cerner Multum, Inc. “Australian Product Information.” O 0

3. “Product Information. Ultram ER (traMADol).” ProCare Pharmaceuticals, Raritan, NJ.

4. “Product Information. Ultram (tramadol).” McNeil Pharmaceutical, Raritan, NJ.

Further information about tramadol 100:

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.